Finally, a Future Without Fear Is Within Your Reach!
Human Pharma Projects
Millions of patients around the world suffer from persistent, infected and potentially life-threatening wounds. They are not only painful, but also restrict the life of every individual. The patients are exhausted – socially, physically and emotionally.
The common cause are bacterial pathogens that hinder the patients‘ pain-free lives. Wound care can rapidly become more complicated when doctors have to combat infections caused by antibiotic-resistant bacteria. Pathogens, such as Staphylococcus aureus, develop resistance to one or more antibiotics.
This makes the treatment of chronic wounds immensely more difficult and results in a serious and permanent health risk for the patient. In Germany alone, over 1 million people suffer from chronic wounds.
Atopic dermatitis is a chronic, relapsing, and lifelong inflammatory and eczematous skin disease. The currently available treatment options are not effective or have significant or adverse side effects. Symptoms include red and dry patches of skin, which may ooze or bleed when scratched, as well as thickening and hardening of the skin.
The cause of AD is still not fully understood. Research suggests that changes in the protective layer of the skin can cause it to become dry, which may lead to damage and inflammation. Scratching the skin can further exacerbate the damage and increase the risk of bacterial infection. Scientists increasingly link Staphylococcus aureus to the severity of atopic dermatitis. In many individuals with severe symptoms, 70% of the skin is colonized with Staphylococcus aureus.
Worldwide, approximately 2.4% of humans suffer from atopic dermatitis, with the majority being children. Like many other chronic disorders, AD can have serious psychological effects on patients, such as depression, anxiety, and social isolation.
Urinary tract infections (UTIs) are infections of the bladder and kidneys. Antibiotics are typically the first line of treatment for UTIs, although there is a rise in the prevalence of resistant bacterial strains.
UTIs are predominantly caused by Escherichia coli strains that are increasingly becoming resistant to antibiotics.
Every year, approximately 150 million UTIs occur worldwide, with a 60% probability of becoming chronic. Women are particularly affected, accounting for over 80% of all cases.
Close to Revenue Projects
Our primary strategic objective is to develop human pharmaceutical products for treating bacterial infections. However, considering the platform nature and superior technology of the Artilysin® platform, as well as for risk mitigation purposes, Lysando has concurrently pursued two projects with significantly shorter development timelines. These projects are anticipated to generate revenue prior to the market launch of our initial human pharmaceutical product:
Acne is caused by sebaceous glands being clogged with dead skin cells and oil from the skin. There are different types of acne like Acne vulgaris or Acne tarde. Acne vulgaris is the most frequent dermatosis in adolescence with a prevalence of almost 90%.
Within these sebaceous glands, Cutibacterium acnes is the most prevalent and abundant species, representing approximately 90% of the local skin microbiome. Although being part of the healthy skin microbiome, C. acnes is directly involved in the disease pathogenesis of acne.
Acne is the most common dermatological disorder worldwide and over 780 million people globally bear the burden of it. Acne causes physical and mental pain for the affected people in many different ways.
Bovine Mastitis is a bacterial infection of the udder in dairy cows. It can present in two ways: Clinical and non-clinical. In non-clinical cases no outside symptoms can be observed, whereas in clinical cases the udder is swollen and red.
The most prevalent bacterial species in Bovine Mastitis are Staphylococcus spp. and E. coli – including a high number of antibiotic resistant strains. Especially multi resistant Staphylococcus aureus (MRSA) is often a cause of infections – not exclusively in agriculture but also in human pharma.
Multidrug resistance is on the rise, especially in intensive animal farming. As a consequence, antibiotics increasingly fail. Infected cows produce less milk and in severe cases all production is lost. The addressable market should reach about 2.4 billion USD by 2030.
You Come In
We are Offering You the Chance to Join Us in Creating a Healthier Future for Us All
Your Support Will Make a Real Difference in the World:
By creating a world where bacterial infections no longer pose a threat to our lives
By protecting everyone in our society and enabling them to live longer and healthier lives
By ensuring that bacterial infections can be treated in a more sustainable and tolerable way
By creating a new standard in medicine, one which takes away the fear of a hospital visit
By stopping the further increase of antibiotic contamination of animal-based food
By reducing the amount of antibiotic residues entering our oceans and environment
Here’s How You Can Support Us
Spread the word and inform your friends and family about us.
Ask your doctors and pharmacists if they are familiar with our technology and encourage them to reach out to us for further information.
Let’s Join Forces!
Want to Do More?